Resistance Genes Underlying the LSA Phenotype of Staphylococcal Isolates from France.

نویسندگان

  • Sophie Tessé
  • François Trueba
  • Nicolas Berthet
  • Chloé Hot
  • Olivier Chesneau
چکیده

There exist numerous genes disseminated by mobile elements that can confer cross-resistance to lincosamides and streptogramin A compounds in staphylococci. This study investigated the nature and means of dissemination of genes responsible for LSA resistance among 24 French clinical isolates screened for reduced susceptibility to lincomycin. The vga(A)v gene was found to be the most prevalent determinant of LSA resistance, while Tn5406 appeared to be its exclusive gene support.

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عنوان ژورنال:
  • Antimicrobial agents and chemotherapy

دوره 57 9  شماره 

صفحات  -

تاریخ انتشار 2013